Role of Dendritic Cell Subsets on HIV-Specific Immunity
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چکیده
DC are key regulators of immunity in view of the fact that they are involved in immune re‐ sponses against infectious diseases, allergy and cancer [1, 2]. Ralph Steinman was awarded the Nobel Prize for Medicine 2011 for DC discovery in 1973 [3]. Steinman and Cohn [3] de‐ scribed a novel cell type in mouse spleen, which they named ́dendritic cell ́ due to their tree-like shape. The major function of DC is the induction of adaptive immunity in the LN.Yet, DC can also interact with innate immune cells, for instance natural killer (NK) and NKT cells [1, 4].
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تاریخ انتشار 2014